QIAN SU LAB
  • Home
  • Our research
    • Autophagy and Mitochondria
    • Chromatin DNA Structure
    • Cardiovascular Interactome
  • Publications
  • Our team
    • Our team
    • Team Photo
    • About Peter Su
    • Our Collaborators
  • News
  • Resources
    • Chromatin DNA Labelling
    • Actin Fluorescent Labelling
    • Motor Protein Purification
    • in vitro Reconstitution
    • Antibody Labelling
    • Single-molecule Tracking
    • Super-resolution Mapping
    • Codes for SM and SR
  • Contact us
  • Intranet
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Welcome to QIAN SU Lab

Laboratory of Quantitative Imaging At
Nanoscale ​with SUper-resolution​​
Chromatin Structure & DNA Replication
Intracellular Membrane Dynamics
Super-Resolution Microscopy
Single-Molecule Imaging
Cardiovascular Disease
The Australia-map like image is an activated human platelet immuno-stained
​towards integrin αIIbβ3 and the image was taken by super-resolution
STochastic Optical Reconstruction Microscopy (STORM).
Image credit: Dr Arnold Ju and Dr Peter SU
Our research bridges applied biomedical engineering with fundamental sciences. It brings new insights to mechanistic questions addressed at single-molecule level by advanced microscopy and acquired with high spatiotemporal resolution. We have developed state-of-art biophysical nanotools, including single-molecule in vitro reconstitution assays, super-resolution microscopy and volumetric imaging methods to visualise the precise structures and pinpoint the molecular mechanisms during important biological processes, including:
i) Developing advanced single-molecule imaging, tracking and manipulation techniques to study motor proteins (kinesin and myosin) and cytoskeleton driven intracellular bio-membrane dynamics and the underlying molecular mechanisms, especially using in vitro re-constitution systems;
ii) Developing and applying cutting-edge super-resolution imaging systems and algorithms (especially STORM and PALM) to resolve the precise structures of subcellular organelles, to map the spatial-temporal distribution of important proteins, to reveal the hierarchical chromatin structures as well as structure-mediated replication and transcription mechanisms in mammalian cell nucleus and bacterial chromatin;
iii) Deciphering the molecular interaction dynamics (termed “molecular interactome”) for the mechanosensor integrin αIIbβ3 during human platelet decision-making process, under clinical trialed drug treatment for cardiovascular diseases, including thrombosis and type 2 diabetes.
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©Copyright 2020. All Rights Reserved.
Site edited by Dr Qian Peter Su
Last update: 01 Jan 2021
Contact us
qian.su@uts.edu.au
​petersq001@gmail.com
Links to
​UTS | Faculty of Engineering and IT |
School of Biomedical Engineering
​
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  • Home
  • Our research
    • Autophagy and Mitochondria
    • Chromatin DNA Structure
    • Cardiovascular Interactome
  • Publications
  • Our team
    • Our team
    • Team Photo
    • About Peter Su
    • Our Collaborators
  • News
  • Resources
    • Chromatin DNA Labelling
    • Actin Fluorescent Labelling
    • Motor Protein Purification
    • in vitro Reconstitution
    • Antibody Labelling
    • Single-molecule Tracking
    • Super-resolution Mapping
    • Codes for SM and SR
  • Contact us
  • Intranet